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</div> <div class="container-fluid clearfix layout_564394 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0); margin-top: 30px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_439253"> <div class="column"> <div class="column visual-conent-title"> <p class="content-title"> 血液外泌体miRNA作为非小细胞癌分子标志物分析</p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_610181" style="margin-top: 0px;"> <div class="column"> <div class="container clearfix layout_148235 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0);"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_369638 text-center" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_13448"> <div class="column"> <div class="col-md-12 layout_455380"> <div class="col-md-2 column"> </div> <div class="col-md-8 column"> <div class="column visual-conent-author visual-inline-block"> <p class="content-author"> <span>作者：</span>admin</p> </div> <div class="column visual-conent-adddate visual-inline-block" style="padding-left: 15px; padding-right: 15px;"> <p class="content-adddate"> <span>添加时间：</span>2019-04-06 13:29:35</p> </div> <div class="column visual-conent-source visual-inline-block"> <p class="content-source"> <span>来源：</span>云序生物</p> </div> <div class="column visual-category-statistics visual-inline-block" style="padding-left: 15px;"> 浏览：<script src="/index.php?case=archive&act=view_js&aid=36"></script></div> </div> <div class="col-md-2 column"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_617573" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_903271"> <div class="column"> <div class="column visual-category-title"> <div class="content_tools_box"> <p class="content_tools"> <a href="javascript:CallPrint('print');">打印本文</a> <a href="javascript:doZoom(14)">小</a> <a href="javascript:doZoom(18)">中</a> <a href="javascript:doZoom(20)">大</a> </p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_43304" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_784828"> <div class="column"> <div class="column visual-conent"> <p><strong>题目</strong>：Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early stage non-small-cell lung cancer using next-generationsequencing</p><p><strong>期刊</strong>：Clinical Cancer Reserach</p><p><strong>影响因子</strong>：8.78</p><p><strong>简介</strong>：本文发现腺癌（AC）和鳞癌（SCC）患者的血浆可分离出肿瘤来源外泌体，其中外泌体miRNA极有希望用于NSCLC早期预测和诊断。文章利用miRNA-seq对46个I期NSCLC患者和42个健康个体的外泌体进行miRNA分析，以鉴定和验证AC和SCC的特异性表达miRNA。结果表明，miR-181-5P、miR-30a-3p、miR-30e-3p和miR-361-5p为AC特异性的；miR-10b-5p、miR-15b-5p和miR-320b为SCC特异性的。后续绘制ROC曲线预测评估三种组合miRNA疾病相关性。事实证明这些miRNA有极大潜力成为NSCLC早期诊断生物标志物。</p><p style="text-align: center;"><img src="/html/upload/images/201904/15563530553353.png" width="780" height="508"/></p></div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_676599" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_158624"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_667472"> <div class="column"> <div class="container clearfix layout_381979"> <div class="column"> <div class=" visual-conent-form"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_886423" style="margin-top: 15px; margin-bottom: 5px;"> <div class="column"> <div class="container clearfix layout_390441"> <div class="column"> <div class="column visual-conent-page"> <div id="page"> <strong>上一篇</strong><a href="/index.php?case=archive&act=show&aid=35">脂肪来源的干细胞分泌外泌体可减轻脂肪炎症和肥胖现象</a> <div class="blank10"> </div> <strong>下一篇</strong><a href="/index.php?case=archive&act=show&aid=37">尿液中的外泌体可作为往后液体活检的分子标志物</a> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_402892" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_939884"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_57479" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_608164"> <div class="column"> <div class="column visual-conent-comment"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_815628" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_771703"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_275539" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_875600"> <div class="column"> <div class="column visual-conent-relevant-list"> <h3> <a><a href='/index.php?case=tag&act=show&tag=%E5%A4%96%E6%B3%8C%E4%BD%93' target='_blank'>外泌体</a> <a href='/index.php?case=tag&act=show&tag=%E8%A1%80%E6%B6%B2' target='_blank'>血液</a> <a href='/index.php?case=tag&act=show&tag=miRNA' target='_blank'>miRNA</a> <small>相关内容</small></a> </h3> <span>——</span> <hr class="featurette-divider" /> <div class="container list-container"> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>21</span> <p> 2019-03</p> </div> <h4> <a title=""新宠"外泌体正式进入临床检验，路还有多远？" href="/index.php?case=archive&act=show&aid=65" target="_blank">"新宠"外泌体正式进…</a> </h4> <p> 一管血检测癌症，是全球医学界共同的梦想。液体活检作为传统活检的替代技术，通过非侵入性的取样方式获得肿瘤信息，辅助癌症治疗，是精准医疗代表性的诊断技术。液体活检的主要检测物包括血液中的循环肿瘤细胞(circulating tumor cells，CTCs)、循环肿瘤DNA(circ… <a href="/index.php?case=archive&act=show&aid=65" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-01</p> </div> <h4> <a title="2018外泌体重量级研究一览，看这篇就够了" href="/index.php?case=archive&act=show&aid=64" target="_blank">2018外泌体重量级研究一览，看这篇就够</a> </h4> <p> 刚过去的2018年，也是外泌体研究热度持续升温的一年，在多个领域均涌现了重大的研究进展。本篇结合Nature、Cell、Cell Metab、Gastroenterology、Science、Nat Rev Mol Cell Biol、Chem Rev发表的重量级文章对2018外…… <a href="/index.php?case=archive&act=show&aid=64" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>20</span> <p> 2019-04</p> </div> <h4> <a title="2019年恩赛尔正式推出外泌体标准化服务" href="/index.php?case=archive&act=show&aid=50" target="_blank">2019年恩赛尔正式推出外泌体标准化服务</a> </h4> <p> 2019年4月厦门恩赛尔生物科技有限公司正式完成平台升级与系统完善，面向工业客户提供标准化的外泌体分离提纯及检测服务。… <a href="/index.php?case=archive&act=show&aid=50" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>01</span> <p> 2019-02</p> </div> <h4> <a title="2018年ncell参与外泌体行业共识制定" href="/index.php?case=archive&act=show&aid=49" target="_blank">2018年ncell参与外泌体行业共识制</a> </h4> <p> 2018年12月公司首席科学家叶国栋博士作为执笔人参与国内首个外泌体行业共识的制定与发布。… <a href="/index.php?case=archive&act=show&aid=49" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-04</p> </div> <h4> <a title="Exosome：揭秘干细胞与免疫细胞如何“对话”" href="/index.php?case=archive&act=show&aid=48" target="_blank">Exosome：揭秘干细胞与免疫细胞如何</a> </h4> <p> 在此网络研讨会中，Pluchino博士讲解了外泌体与神经干细胞和神经元前体细胞发生信号传导的情况，以及它们在神经炎性疾病中的作用。此外，他还谈及外泌体靶向治疗的未来。… <a href="/index.php?case=archive&act=show&aid=48" target="_blank">[了解更多]</a> </p> </div> </div> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="view-html"> <div class="container-fluid clearfix layout_971667" style="padding-top: 60px; padding-bottom: 60px; background-color: rgb(51, 51, 51); color: rgb(255, 255, 255);"> <div class="column"> <div class="container clearfix layout_976890 text-bold" style="font-size: 20px; padding-top: 20px; padding-bottom: 20px;"> <div class="column"> 厦门恩赛尔生物科技有限公司位于国家级企业孵化基地海沧生物医药产业园，参照GMP标准建设有完善的研发生产实验室并通过厦门市食品药品质量检查研究院依据国家标准GB50457-2008的洁净级别检测，团队汇聚大帮技术精湛的博士、硕士人员及外籍科学家，并由多名“千人计划”专家作为技术顾问，同时兼具遗传咨询师、系统架构师、注册审核员等各类人才，具备专业的科学研究和服务咨询能力。 企业定位为工业客户提供标准化的外泌体分离提纯及检测服务，并且在该项技术领域拥有创新突破和权威认可，作为首席科学家兼企业法人代表，叶国栋博士在肿瘤及血液检测技术领域有十数年的技术积累，参与并执笔国内首个《外泌体研究、转化和临床应用专家共识》，未来将继续促进该项标准化技术的落地，为外泌体行业的蓬勃发展贡献一份力量。</div> </div> <div class="container clearfix layout_292464"> <div class="column"> <div class="col-md-3 layout_694949"> <div class="row 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class="modal fade bs-example-modal-lg-shopping" tabindex="-1" role="dialog" aria-labelledby="mySmallModalLabel"> <div class="modal-dialog modal-sm"> <div class="modal-content"> </div> </div> </div> <!-- s/shopping 购物车 --> <div class="servers"> <!--[if (gte IE 7)|!(IE)]><!--> <!-- 在线客服 --> <style type="text/css"> .izl-rmenu{position:fixed; left:0; margin-right:20px; bottom:0px; padding-bottom:0px; z-index:999; } .izl-rmenu .sbtn{width:72px; height:73px; margin-bottom:1px; cursor:pointer; position:relative;} .izl-rmenu .btn-qq{background:url(/template/default_visual/skin/images/servers/metro_color/r_qq.png) 0px 0px no-repeat; background-color:#999;color:#FFF;} .izl-rmenu .btn-qq:hover{background-color:#444;color:#FFF;} .izl-rmenu .btn-qq .qq{background-color:#444; position:absolute; width:160px; right:-160px; top:0px; line-height:73px; color:#FFF; font-size:18px; text-align:center; display:none;} .izl-rmenu .btn-qq a {color:#FFF;font-size:14px;} .izl-rmenu 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a.btn-ali:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_ali.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-wangwang{background:url(/template/default_visual/skin/images/servers/metro_color/r_wangwang.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-wangwang:hover{background-color:#444;} .izl-rmenu a.btn-wangwang,.izl-rmenu a.btn-wangwang:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_wangwang.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-skype{background:url(/template/default_visual/skin/images/servers/metro_color/r_skype.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-skype:hover{background-color:#444;} .izl-rmenu a.btn-skype,.izl-rmenu a.btn-skype:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_skype.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-web{background:url(/template/default_visual/skin/images/servers/metro_color/r_web.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-web:hover{background-color:#444;} .izl-rmenu a.btn-web,.izl-rmenu a.btn-web:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_web.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-top{background:url(/template/default_visual/skin/images/servers/metro_color/r_top.png) 0px 0px no-repeat; background-color:#999; display:none;} .izl-rmenu .btn-top:hover{background-color:#444;} </style> <script language="javascript" type="text/javascript"> $(function(){ var tophtml="<div id=\"izl_rmenu\" class=\"izl-rmenu\"><div class=\"sbtn btn-qq\"><div class=\"qq\"><a rel=\"nofollow\" target=\"_blank\" href=\"tencent://Message/?Uin=226976731&websiteName=http://www.ncell.com.cn=&Menu=yes\">客服一</a><br /><a rel=\"nofollow\" target=\"_blank\" href=\"tencent://Message/?Uin=525274299&websiteName=http://www.ncell.com.cn=&Menu=yes\">客服二</a></div></div><div class=\"sbtn btn-wx\"><img class=\"pic\" src=\"/html/upload/images/201904/15565910929476.png\" onclick=\"window.location.href=\'http:\'\"/></div><div class=\"sbtn btn-phone\"><div class=\"phone\">0592-5792117</div></div><div class=\"sbtn btn-top\"></div></div>"; $("#top").html(tophtml); $("#izl_rmenu").each(function(){ $(this).find(".btn-qq").mouseenter(function(){ $(this).find(".qq").fadeIn("fast"); }); $(this).find(".btn-qq").mouseleave(function(){ $(this).find(".qq").fadeOut("fast"); }); $(this).find(".btn-wx").mouseenter(function(){ $(this).find(".pic").fadeIn("fast"); }); $(this).find(".btn-wx").mouseleave(function(){ $(this).find(".pic").fadeOut("fast"); }); $(this).find(".btn-phone").mouseenter(function(){ $(this).find(".phone").fadeIn("fast"); }); $(this).find(".btn-phone").mouseleave(function(){ $(this).find(".phone").fadeOut("fast"); }); $(this).find(".btn-top").click(function(){ $("html, body").animate({ "scroll-top":0 },"fast"); }); }); var lastRmenuStatus=false; $(window).scroll(function(){//bug var _top=$(window).scrollTop(); if(_top>200){ $("#izl_rmenu").data("expanded",true); }else{ $("#izl_rmenu").data("expanded",false); } if($("#izl_rmenu").data("expanded")!=lastRmenuStatus){ lastRmenuStatus=$("#izl_rmenu").data("expanded"); if(lastRmenuStatus){ $("#izl_rmenu .btn-top").slideDown(); }else{ $("#izl_rmenu .btn-top").slideUp(); } } }); }); </script> <div id="top"></div><![endif]--> <!-- 短信 --> </div> <div class="servers-wap"> <link href="/template/default_visual/skin/css/wap/wap6.css" rel="stylesheet" /> <style type="text/css"> #plug-wrap { position: fixed; top: 0; left: 0; width: 100%; height: 100%; background: rgba(0, 0, 0, 0); z-index:800; } .top_bar { position:fixed; bottom:0; right:0px; z-index:900; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); font-family: 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font-size:20px; display: block; height: 100%; line-height: 33px; text-align: center; } .top_menu>li>a label{ display:none; } .top_menu>li a img { display: block; width: 22px; height: 22px; text-indent: -999px; position: absolute; top: 50%; left: 50%; margin-top: -11px; margin-left: -11px; } .top_menu>li.on:nth-of-type(1) { -webkit-transform: translate(-0, -100px) rotate(720deg); } .top_menu>li.on:nth-of-type(2) { -webkit-transform: translate(-47px, -81px) rotate(720deg); } .top_menu>li.on:nth-of-type(3) { -webkit-transform: translate(-81px, -45px) rotate(720deg); } .top_menu>li.on:nth-of-type(4) { -webkit-transform: translate(-100px, 0) rotate(720deg); } #sharemcover { position: fixed; top: 0; left: 0; width: 100%; height: 100%; background: rgba(0, 0, 0, 0.7); display: none; z-index: 20000; } #sharemcover img { position: fixed; right: 18px; top: 5px; width: 260px; height: 180px; z-index: 20001; border:0; } </style> <div class="top_bar" style="-webkit-transform:translate3d(0,0,0)"> <nav> <ul id="top_menu" class="top_menu"> <input type="checkbox" id="plug-btn" class="plug-menu themeStyle" style="background-image:url('/template/default_visual/skin/images/wap/plug.png');border:0px;"> <li class="themeStyle out" style="background:"> <a href="tel:0592-5792117"><img src="/template/default_visual/skin/images/wap/plugmenu1.png"><label>电 话</label></a> </li> <li class="themeStyle out" style="background:"> <a href="sms:13599994885"><img src="/template/default_visual/skin/images/wap/plugmenu3.png"><label>短信</label></a> </li> <li class="themeStyle out" style="background:"> <a href="mqqwpa://im/chat?chat_type=wpa&uin=226976731&version=1&src_type=web&web_src=http://www.ncell.com.cn" id="btn_fenxiang"><img src="/template/default_visual/skin/images/wap/plugmenu5.png"><label>QQ号码</label></a> </li> <li class="themeStyle out" style="background:"> <a href="/index.php?case=guestbook&act=index"><img src="/template/default_visual/skin/images/wap/plugmenu6.png"><label>留言</label></a> </li> </ul> </nav> </div> <div id="plug-wrap" style="display: none;" ></div> <script> $(function(){ $(".plug-menu").click(function(){ var li = $(this).parents('ul').find('li'); if(li.attr("class") == "themeStyle on"){ li.removeClass("themeStyle on"); li.addClass("themeStyle out"); }else{ li.removeClass("themeStyle out"); li.addClass("themeStyle on"); } }); }); </script> </div> <!-- 导航下拉缩小高度 --> <script type="text/javascript"> <!-- $(document).ready(function(){ $(window).scroll(function() { var top = $(".carousel-indicators,.visual-category-img").offset().top; //获取指定位置 var scrollTop = $(window).scrollTop(); //获取当前滑动位置 if(scrollTop > top){ //滑动到该位置时执行代码 $(".navbar").addClass("active"); }else{ $(".navbar").removeClass("active"); } }); }); $(function(){ var cubuk_seviye = $(document).scrollTop(); var header_yuksekligi = $('.navbar').outerHeight(); $(window).scroll(function() { var kaydirma_cubugu = $(document).scrollTop(); if (kaydirma_cubugu > header_yuksekligi){$('.navbar').addClass('gizle');} else {$('.navbar').removeClass('gizle');} if (kaydirma_cubugu > cubuk_seviye){$('.navbar').removeClass('sabit');} else {$('.navbar').addClass('sabit');} cubuk_seviye = $(document).scrollTop(); }); }); //--> </script> <!-- 鼠标滑过展开一级菜单/一级菜单可点击 --> <script type="text/javascript"> $(function () { $(".dropdown,.dropdown-submenu").mouseover(function () { $(this).addClass("open"); }); $(".dropdown,.dropdown-submenu").mouseleave(function(){ $(this).removeClass("open"); }) }); $(document).ready(function(){ var _width = $(window).width(); if(_width < 768){ $("#navbar a.toogle").click(function(){ event.preventDefault(); }); } }); </script> <!-- wow动态效果 --> <link rel="stylesheet" href="/template/default_visual/skin/css/animate.min.css" /> <script src="/template/default_visual/skin/js/wow.min.js"></script> <script> if (!(/msie [6|7|8|9]/i.test(navigator.userAgent))){ new WOW().init(); }; </script> <!-- 导航置顶CSS --> <style type="text/css"> .navbar { padding-right:0; padding-left:0;position:fixed; right:0; left:0; z-index:1030; border-radius:0; } @media (max-width: 768px) { #bootstrap-touch-slider {margin-top:62px;} #navbar {margin-top:62px;} .navbar>.container .navbar-brand, .navbar>.container-fluid .navbar-brand {margin-left:0px;} } @media (max-width: 468px) { #bootstrap-touch-slider {margin-top:62px;} } </style> <script> $(document).ready(function() { $("#owl-demo").owlCarousel({ items : 3, lazyLoad : true, navigation : true }); }); </script> <!-- Bootstrap core Javascript ================================================== --> <!-- Placed at the end of the document so the pages load faster --> <script src="/template/default_visual/skin/js/bootstrap.min.js"></script> <!-- Just to make our placeholder images work. 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