</noscript> <script> function stop(){ return false; } document.oncontextmenu=stop; </script> <div class="view-html"> <div class="container-fluid clearfix column navbar navbar-default layout_152551"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false"> <span class="sr-only">网站名称</span><span class="icon-bar"></span><span class="icon-bar"></span><span class="icon-bar"></span> </button> <div class="container"> <div id="navbar" class="navbar-collapse collapse"> <ul class="nav navbar-nav"> <li class="oen"><a href="/">网站首页</a></li> <li class="oen dropdown"> <a href="/index.php?case=archive&act=list&catid=21" class="toogle" >产品列表<span class="caret"></span></a> <ul class="two dropdown-menu"> <li> <a title="动物外泌体" href="/index.php?case=archive&act=list&catid=22" >动物外泌体</a> </li> <li> <a title="植物外泌体" href="/index.php?case=archive&act=list&catid=23" >植物外泌体</a> </li> <li> <a title="微生物外泌体" href="/index.php?case=archive&act=list&catid=24" >微生物外泌体</a> </li> </ul> </li> <li class="oen dropdown"> <a href="/index.php?case=archive&act=list&catid=3" class="toogle" >服务项目<span class="caret"></span></a> <ul class="two dropdown-menu"> <li> <a title="超速离心" href="/index.php?case=archive&act=list&catid=15" >超速离心</a> </li> <li> <a title="电镜拍摄" href="/index.php?case=archive&act=list&catid=16" >电镜拍摄</a> </li> <li> <a title="粒径分析" href="/index.php?case=archive&act=list&catid=17" >粒径分析</a> </li> <li> <a title="蛋白检测" href="/index.php?case=archive&act=list&catid=18" >蛋白检测</a> </li> </ul> </li> <li class="oen active dropdown"> <a href="/index.php?case=archive&act=list&catid=2" class="toogle" >研究前沿<span class="caret"></span></a> <ul class="two dropdown-menu"> <li> <a title="行业资讯" href="/index.php?case=archive&act=list&catid=13" >行业资讯</a> </li> <li> <a title="技术方法" href="/index.php?case=archive&act=list&catid=10" >技术方法</a> </li> <li> <a title="文献资料" href="/index.php?case=archive&act=list&catid=6" >文献资料</a> </li> <li> <a title="数据共享" href="/index.php?case=archive&act=list&catid=8" >数据共享</a> </li> </ul> </li> <li class="oen dropdown"> <a href="/index.php?case=archive&act=list&catid=1" class="toogle" >关于我们<span class="caret"></span></a> <ul class="two dropdown-menu"> <li> <a title="平台介绍" href="/index.php?case=archive&act=list&catid=4" >平台介绍</a> </li> <li> <a title="团队成员" href="/index.php?case=archive&act=list&catid=11" >团队成员</a> </li> <li> <a title="发展历程" href="/index.php?case=archive&act=list&catid=12" >发展历程</a> </li> <li> <a title="送样须知" href="/index.php?case=archive&act=list&catid=19" >送样须知</a> </li> <li> <a title="常见问题" href="/index.php?case=archive&act=list&catid=20" >常见问题</a> </li> </ul> </li> <li class="oen"> <a href="/index.php?case=archive&act=list&catid=5" >联系我们</a> </li> <li class="oen"> <a href="/index.php?case=archive&act=list&catid=14" >案例展示</a> </li> </ul> </div><div class="row layout_315462" style="float: left;"> <a href="" class="navbar-brand text-center"><img src="/html/upload/images/201904/15563778334246.jpg" class="img-responsive" alt="厦门恩赛尔生物科技有限公司（外泌体标准化服务平台）"></a> </div> </div> <div class="top-nav-right navbar-right layout_602435"> <ul> <li id="fat-menu" class="dropdown"> <a class="dropdown-toggleglyphicon glyphicon glyphicon-globe" data-toggle="dropdown" role="button" aria-expanded="false"></a> <ul class="dropdown-menu" aria-labelledby="drop3"> <li> <a id="StranLink" name="StranLink">繁體</a> </li> <li> <a target="_blank">公司网站</a> </li> </ul> </li> <li class="glyphicon glyphicon-search" data-toggle="modal" data-target=".bs-example-modal-lg-search" aria-hidden="true"> </li> </ul> </div> </div> </div> <div class="view-html"> <div class="container-fluid clearfix layout_262063"> <div class="column"> <div class="column visual-slide"> <!-- Bootstrap bootstrap-touch-cslider Slider Main Style Sheet --> <div id="bootstrap-touch-cslider" class="carousel bs-slider fade row control-round indicators-line" data-ride="carousel" data-pause="hover" data-interval="5000"> <!-- Indicators --> <ol class="carousel-indicators"> <li data-target="#bootstrap-touch-cslider" data-slide-to="0" class="active"></li> </ol> <!-- Wrapper For Slides --> <div class="carousel-inner" role="listbox"> <!-- Second Slide --> <div class="item active"> <!-- Slide Background --> <img src="/html/upload/images/201904/15564153413583.png" alt="" class="slide-image"> </div> <!-- End of Slide --> </div><!-- End of Wrapper For Slides --> </div></div> </div> </div> <div class="container-fluid clearfix layout_67908" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_863630"> <div class="column"> <div class="column visual-category-notifications"> <nav class="sub_menu"> <ol class="breadcrumb"> <span class="glyphicon glyphicon-list"></span> <li><a href="/">网站首页</a></li> <li><a title="研究前沿" href="/index.php?case=archive&act=list&catid=2">研究前沿</a></li> <li><a title="行业资讯" href="/index.php?case=archive&act=list&catid=13">行业资讯</a></li> </ol> </nav> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_564394 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0); margin-top: 30px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_439253"> <div class="column"> <div class="column visual-conent-title"> <p class="content-title"> Cell同期发表多篇外泌体与细胞外RNA文章</p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_610181" style="margin-top: 0px;"> <div class="column"> <div class="container clearfix layout_148235 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0);"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_369638 text-center" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_13448"> <div class="column"> <div class="col-md-12 layout_455380"> <div class="col-md-2 column"> </div> <div class="col-md-8 column"> <div class="column visual-conent-author visual-inline-block"> <p class="content-author"> <span>作者：</span>企鹅</p> </div> <div class="column visual-conent-adddate visual-inline-block" style="padding-left: 15px; padding-right: 15px;"> <p class="content-adddate"> <span>添加时间：</span>2019-05-20 17:14:54</p> </div> <div class="column visual-conent-source visual-inline-block"> <p class="content-source"> <span>来源：</span>外泌体资讯网</p> </div> <div class="column visual-category-statistics visual-inline-block" style="padding-left: 15px;"> 浏览：<script src="/index.php?case=archive&act=view_js&aid=4"></script></div> </div> <div class="col-md-2 column"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_617573" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_903271"> <div class="column"> <div class="column visual-category-title"> <div class="content_tools_box"> <p class="content_tools"> <a href="javascript:CallPrint('print');">打印本文</a> <a href="javascript:doZoom(14)">小</a> <a href="javascript:doZoom(18)">中</a> <a href="javascript:doZoom(20)">大</a> </p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_43304" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_784828"> <div class="column"> <div class="column visual-conent"> <p style="text-align:center"><a href="http://www.exosomemed.com/wp-content/uploads/2019/04/4.8-2-1.png" style="color: rgb(33, 154, 68); text-decoration-line: none; transition: color 0.5s;"><img class="alignnone size-medium wp-image-5764" src="/html/upload/images/201904/15562879395047.png" alt="4.8-2-1" width="600" height="500" title="4.8-2-1"/></a></p><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px; white-space: normal; text-align: left;"><strong> 最新一期的Cell杂志上，同期发表了7篇外泌体与细胞外RNA（exRNA）文章</strong>。内容包括外泌体PD-L1、外泌体组成重新评估、exRNA在多种体液/多种细胞外组分中的精细分析等。其中，2篇关于外泌体的Featured Articles，2篇关于exRNA的Resources，perspective、minireview和preview各1篇。</p><ol style="list-style-type: none;" class=" list-paddingleft-2"><li><p><br/></p></li><li><p style="text-align:center"><a href="http://www.exosomemed.com/wp-content/uploads/2019/04/4.8-2-2.png" style="color: rgb(33, 154, 68); text-decoration-line: none; transition: color 0.5s;"><img class="alignnone size-medium wp-image-5765" src="/html/upload/images/201904/15562879393986.png" alt="4.8-2-2" width="600" height="500" title="4.8-2-2"/></a></p></li><li><p style="text-align: center;"><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">Poggio M, Hu T, Pai CC, Chu B, Belair CD, Chang A, Montabana E, Lang UE, Fu Q, Fong L, Blelloch R. Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. </span><strong style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"><em><span style="text-decoration-line: underline;">Cell</span></em></strong><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">. 2019 Apr 4;177(2):414-427.e13. doi: 10.1016/j.cell.2019.02.016.</span></p></li><li><p><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"> </span><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"> 该研究发现肿瘤来源的外泌体上的PD-L1参与了肿瘤细胞的免疫治疗逃避。重要的是，对于一些PD-L1抗体治疗效果不佳的肿瘤类型，通过抑制外泌体PD-L1分泌并同时进行PD-L1抗体治疗，能够实现良好的抗肿瘤免疫治疗。</span></p></li><li><p><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"></span><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">前期详细报道：</span><a href="http://www.exosomemed.com/5751.html" style="font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px; color: rgb(33, 154, 68); transition: color 0.5s;">Cell大发现丨抑制外泌体PD-L1的分泌有助于肿瘤免疫治疗</a></p></li></ol><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px; white-space: normal;"><br/></p><ol style="list-style-type: none;" class=" list-paddingleft-2"><li><p style="text-align:center"><a href="http://www.exosomemed.com/wp-content/uploads/2019/04/4.8-2-3.png" style="color: rgb(33, 154, 68); text-decoration-line: none; transition: color 0.5s;"><img class="alignnone size-medium wp-image-5766" src="/html/upload/images/201904/15562879412836.png" alt="4.8-2-3" width="600" height="500" title="4.8-2-3"/></a></p></li><li><p style="text-align: center;"><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">Jeppesen DK, Fenix AM, Franklin JL, Higginbotham JN, Zhang Q, Zimmerman LJ, Liebler DC, Ping J, Liu Q, Evans R, Fissell WH, Patton JG, Rome LH, Burnette DT, Coffey RJ. Reassessment of Exosome Composition. </span><strong style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"><em><span style="text-decoration-line: underline;">Cell</span></em></strong><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">. 2019 Apr 4;177(2):428-445.e18. doi: 10.1016/j.cell.2019.02.029.</span></p></li><li><p><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"> </span><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">该研究根据严格的分离方法对外泌体组成进行了重新评估，确定了蛋白质、RNA和DNA在小细胞外囊泡和非囊泡细胞外物质之间的差异分布，并确定小细胞外囊泡不是活跃的DNA释放载体，annexin A1是经典质膜形成的微泡的一个标志蛋白。</span></p></li><li><p><span style="letter-spacing: 1.6px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif;">详细报道见本期头条。</span></p></li></ol><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px; white-space: normal; line-height: normal;"> </p><ol style="list-style-type: none;" class=" list-paddingleft-2"><li><p><br/></p></li><li><p style="text-align:center"><a href="http://www.exosomemed.com/wp-content/uploads/2019/04/4.8-2-4.png" style="color: rgb(33, 154, 68); text-decoration-line: none; transition: color 0.5s;"><img class="alignnone size-medium wp-image-5767" src="/html/upload/images/201904/15562879411455.png" alt="4.8-2-4" width="600" height="400" title="4.8-2-4"/></a></p></li><li><p style="text-align: center;"><span style="font-family: 微软雅黑, "Microsoft YaHei"; font-size: 10px;">Pluchino S, Smith JA. Explicating Exosomes: Reclassifying the Rising Stars of Intercellular Communication. <strong><em><span style="font-family: 微软雅黑, "Microsoft YaHei"; text-decoration-line: underline;">Cell</span></em></strong>. 2019 Apr 4;177(2):225-227. doi: 10.1016/j.cell.2019.03.020.</span></p></li><li><p><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px; font-size: 16px;">这是一篇针对Reassessment of Exosome Composition研究文章的preview。</span><br/></p></li></ol><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px; white-space: normal;"> </p><p><br/></p><ol style="list-style-type: none;" class=" list-paddingleft-2"><li><p style="text-align:center"><a href="http://www.exosomemed.com/wp-content/uploads/2019/04/4.8-2-5.png" style="color: rgb(33, 154, 68); text-decoration-line: none; transition: color 0.5s;"><img class="alignnone size-medium wp-image-5768" src="/html/upload/images/201904/15562879426827.png" alt="4.8-2-5" width="600" height="500" title="4.8-2-5"/></a></p></li><li><p style="text-align: center;"><span style="font-family: 微软雅黑, "Microsoft YaHei"; font-size: 10px;">Murillo OD, Thistlethwaite W, Rozowsky J, Subramanian SL, Lucero R, Shah N, Jackson AR, Srinivasan S, Chung A, Laurent CD, Kitchen RR, Galeev T, Warrell J, Diao JA, Welsh JA, Hanspers K, Riutta A, Burgstaller-Muehlbacher S, Shah RV, Yeri A, Jenkins LM, Ahsen ME, Cordon-Cardo C, Dogra N, Gifford SM, Smith JT, Stolovitzky G, Tewari AK, Wunsch BH, Yadav KK, Danielson KM, Filant J, Moeller C, Nejad P, Paul A, Simonson B, Wong DK, Zhang X, Balaj L, Gandhi R, Sood AK, Alexander RP, Wang L, Wu C, Wong DTW, Galas DJ, Van Keuren-Jensen K, Patel T, Jones JC, Das S, Cheung KH, Pico AR, Su AI, Raffai RL, Laurent LC, Roth ME, Gerstein MB, Milosavljevic A. exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids. <strong><em><span style="font-family: 微软雅黑, "Microsoft YaHei"; text-decoration-line: underline;">Cell</span></em></strong>. 2019 Apr 4;177(2):463-477.e15. doi: 10.1016/j.cell.2019.02.018.</span></p></li><li><p><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px;"> 该报道展示了一份来自五种人类生物体液(血清、血浆、脑脊液、唾液和尿液)的细胞外RNA图谱，显示了六种细胞外RNA载体类型，包括囊泡载体和非囊泡载体。</span><br/></p></li></ol><p><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px;"> 为了开发细胞外RNA (exRNA)介导的细胞间通讯图谱，NIH细胞外RNA通讯联盟（Extracellular RNA Communication Consortium）创建了exRNA图谱资源(https://exrna-atlas.org)。Atlas版本4P1包含来自19项研究的5309个exRNA-seq和exRNA qPCR概要文件，以及一套分析和可视化工具。通过分析，该研究得到了一个包含六种exRNA类型(CT1、CT2、CT3A、CT3B、CT3C、CT4)的模型，每种exRNA类型都可以在多种生物体液(血清、血浆、脑脊液、唾液、尿液)中检测到。五种exRNA类型与已知的囊泡和非囊泡(脂蛋白和核糖核酸蛋白) exRNA载体有关。</span></p><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px; white-space: normal;"> </p><ol style="list-style-type: none;" class=" list-paddingleft-2"><li><p style="text-align:center"><a href="http://www.exosomemed.com/wp-content/uploads/2019/04/4.8-2-6.png" style="color: rgb(33, 154, 68); text-decoration-line: none; transition: color 0.5s;"><img class="alignnone size-medium wp-image-5769" src="/html/upload/images/201904/15562879433499.png" alt="4.8-2-6" width="600" height="500" title="4.8-2-6"/></a></p></li><li><p style="text-align: center;"><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">Srinivasan S, Yeri A, Cheah PS, Chung A, Danielson K, De Hoff P, Filant J, Laurent CD, Laurent LD, Magee R, Moeller C, Murthy VL, Nejad P, Paul A, Rigoutsos I, Rodosthenous R, Shah RV, Simonson B, To C1, Wong D, Yan IK, Zhang X, Balaj L, Breakefield XO, Daaboul G, Gandhi R, Lapidus J, Londin E, Patel T, Raffai RL, Sood AK, Alexander RP, Das S, Laurent LC. Small RNA Sequencing across Diverse Biofluids Identifies Optimal Methods for exRNA Isolation. </span><strong style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"><em><span style="text-decoration-line: underline;">Cell</span></em></strong><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">. 2019 Apr 4;177(2):446-462.e16. doi: 10.1016/j.cell.2019.03.024.</span></p></li><li><p><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"> </span><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">由于缺乏关于细胞外RNA (exRNA)分离方法性能的认识，导致研究的重复性差，阻碍了exRNA领域的进展。通过对5种生物液体中10种exRNA分离方法的系统比较，发现所得到的小RNA-seq图谱的复杂性和重现性存在显著差异。每种方法对不同的exRNA载体亚类的相对效率是通过估计细胞外囊泡(EV)-、核糖核蛋白(RNP)-和高密度脂蛋白(HDL)特异性miRNA在每个图谱中的比例来确定的。开发了一种基于web的交互式应用程序(miRDaR)，以帮助研究人员为他们的研究选择最佳的exRNA分离方法。这些结果将提高可重复性，并促进exRNA生物标志物的进一步发展。</span></p></li></ol><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px; white-space: normal;"><span style="font-size: 16px;"> </span></p><p><br/></p><ol style="list-style-type: none;" class=" list-paddingleft-2"><li><p style="text-align:center"><a href="http://www.exosomemed.com/wp-content/uploads/2019/04/4.8-2-7.png" style="color: rgb(33, 154, 68); text-decoration-line: none; transition: color 0.5s;"><img class="alignnone size-medium wp-image-5770" src="/html/upload/images/201904/15562879442734.png" alt="4.8-2-7" width="600" height="500" title="4.8-2-7"/></a></p></li><li><p style="text-align: center;"><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">Das S; Extracellular RNA Communication Consortium, Ansel KM, Bitzer M, Breakefield XO, Charest A, Galas DJ, Gerstein MB, Gupta M, Milosavljevic A, McManus MT, Patel T, Raffai RL, Rozowsky J, Roth ME, Saugstad JA, Van Keuren-Jensen K, Weaver AM, Laurent LC. The Extracellular RNA Communication Consortium: Establishing Foundational Knowledge and Technologies for Extracellular RNA Research. </span><strong style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"><em><span style="text-decoration-line: underline;">Cell</span></em></strong><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">. 2019 Apr 4;177(2):231-242. doi: 10.1016/j.cell.2019.03.023. Review.</span></p></li><li><p><span style="font-size: 10px; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;"> </span><span style="color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px;">这是一篇关于exRNA的perspective。细胞外RNA通讯联盟（ERCC）的启动是为了加快细胞外RNA (exRNA)生物学新领域的进展，并确定exRNAs及其载体，包括细胞外小泡(EVs)是否能够介导细胞间通讯并用于临床应用。</span></p></li></ol><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px; white-space: normal;"> </p><ol style="list-style-type: none;" class=" list-paddingleft-2"><li><p style="text-align:center"><a href="http://www.exosomemed.com/wp-content/uploads/2019/04/4.8-2-8.png" style="color: rgb(33, 154, 68); text-decoration-line: none; transition: color 0.5s;"><img class="alignnone size-medium wp-image-5771" src="/html/upload/images/201904/15562879457906.png" alt="4.8-2-8" width="600" height="500" title="4.8-2-8"/></a></p></li></ol><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; font-size: medium; letter-spacing: 1.6px; white-space: normal; text-align: center;"><span style="font-size: 10px;">Lässer C. Mapping Extracellular RNA Sheds Lights on Distinct Carriers. <strong style="white-space: normal;"><em><span style="text-decoration-line: underline;">Cell</span></em></strong>. 2019 Apr 4;177(2):228-230. doi: 10.1016/j.cell.2019.03.027.</span></p><p style="margin-top: 2em; margin-bottom: 2em; color: rgb(51, 51, 51); font-family: "Microsoft Yahei", 微软雅黑, "Comic Sans MS", "MS PGothic", Helvetica, Arial, sans-serif; letter-spacing: 1.6px; white-space: normal;"><span style="letter-spacing: 1.6px; font-size: 12px;"> </span><span style="font-size: 16px; letter-spacing: 1.6px;">这是一篇关于exRNA的minireview。</span></p><p><br/></p></div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_676599" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_158624"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_667472"> <div class="column"> <div class="container clearfix layout_381979"> <div class="column"> <div class=" visual-conent-form"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_886423" style="margin-top: 15px; margin-bottom: 5px;"> <div class="column"> <div class="container clearfix layout_390441"> <div class="column"> <div class="column visual-conent-page"> <div id="page"> <strong>上一篇</strong>无 <div class="blank10"> </div> <strong>下一篇</strong><a href="/index.php?case=archive&act=show&aid=59">暨南大学医学院：唾液外泌体中的嵌合RNA可作为食管癌诊疗的生物标志物</a> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_402892" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_939884"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_57479" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_608164"> <div class="column"> <div class="column visual-conent-comment"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_815628" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_771703"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_275539" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_875600"> <div class="column"> <div class="column visual-conent-relevant-list"> <h3> <a><a href='/index.php?case=tag&act=show&tag=%E5%A4%96%E6%B3%8C%E4%BD%93' target='_blank'>外泌体</a> <a href='/index.php?case=tag&act=show&tag=%E7%BB%86%E8%83%9E%E5%A4%96RNA' target='_blank'>细胞外RNA</a> <a href='/index.php?case=tag&act=show&tag=exRNA' target='_blank'>exRNA</a> <small>相关内容</small></a> </h3> <span>——</span> <hr class="featurette-divider" /> <div class="container list-container"> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>21</span> <p> 2019-03</p> </div> <h4> <a title=""新宠"外泌体正式进入临床检验，路还有多远？" href="/index.php?case=archive&act=show&aid=65" target="_blank">"新宠"外泌体正式进…</a> </h4> <p> 一管血检测癌症，是全球医学界共同的梦想。液体活检作为传统活检的替代技术，通过非侵入性的取样方式获得肿瘤信息，辅助癌症治疗，是精准医疗代表性的诊断技术。液体活检的主要检测物包括血液中的循环肿瘤细胞(circulating tumor cells，CTCs)、循环肿瘤DNA(circ… <a href="/index.php?case=archive&act=show&aid=65" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-01</p> </div> <h4> <a title="2018外泌体重量级研究一览，看这篇就够了" href="/index.php?case=archive&act=show&aid=64" target="_blank">2018外泌体重量级研究一览，看这篇就够</a> </h4> <p> 刚过去的2018年，也是外泌体研究热度持续升温的一年，在多个领域均涌现了重大的研究进展。本篇结合Nature、Cell、Cell Metab、Gastroenterology、Science、Nat Rev Mol Cell Biol、Chem Rev发表的重量级文章对2018外…… <a href="/index.php?case=archive&act=show&aid=64" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>20</span> <p> 2019-04</p> </div> <h4> <a title="2019年恩赛尔正式推出外泌体标准化服务" href="/index.php?case=archive&act=show&aid=50" target="_blank">2019年恩赛尔正式推出外泌体标准化服务</a> </h4> <p> 2019年4月厦门恩赛尔生物科技有限公司正式完成平台升级与系统完善，面向工业客户提供标准化的外泌体分离提纯及检测服务。… <a href="/index.php?case=archive&act=show&aid=50" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>01</span> <p> 2019-02</p> </div> <h4> <a title="2018年ncell参与外泌体行业共识制定" href="/index.php?case=archive&act=show&aid=49" target="_blank">2018年ncell参与外泌体行业共识制</a> </h4> <p> 2018年12月公司首席科学家叶国栋博士作为执笔人参与国内首个外泌体行业共识的制定与发布。… <a href="/index.php?case=archive&act=show&aid=49" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-04</p> </div> <h4> <a title="Exosome：揭秘干细胞与免疫细胞如何“对话”" href="/index.php?case=archive&act=show&aid=48" target="_blank">Exosome：揭秘干细胞与免疫细胞如何</a> </h4> <p> 在此网络研讨会中，Pluchino博士讲解了外泌体与神经干细胞和神经元前体细胞发生信号传导的情况，以及它们在神经炎性疾病中的作用。此外，他还谈及外泌体靶向治疗的未来。… <a href="/index.php?case=archive&act=show&aid=48" target="_blank">[了解更多]</a> </p> </div> </div> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="view-html"> <div class="container-fluid clearfix layout_971667" style="padding-top: 60px; padding-bottom: 60px; background-color: rgb(51, 51, 51); color: rgb(255, 255, 255);"> <div class="column"> <div class="container clearfix layout_976890 text-bold" style="font-size: 20px; padding-top: 20px; padding-bottom: 20px;"> <div class="column"> 厦门恩赛尔生物科技有限公司位于国家级企业孵化基地海沧生物医药产业园，参照GMP标准建设有完善的研发生产实验室并通过厦门市食品药品质量检查研究院依据国家标准GB50457-2008的洁净级别检测，团队汇聚大帮技术精湛的博士、硕士人员及外籍科学家，并由多名“千人计划”专家作为技术顾问，同时兼具遗传咨询师、系统架构师、注册审核员等各类人才，具备专业的科学研究和服务咨询能力。 企业定位为工业客户提供标准化的外泌体分离提纯及检测服务，并且在该项技术领域拥有创新突破和权威认可，作为首席科学家兼企业法人代表，叶国栋博士在肿瘤及血液检测技术领域有十数年的技术积累，参与并执笔国内首个《外泌体研究、转化和临床应用专家共识》，未来将继续促进该项标准化技术的落地，为外泌体行业的蓬勃发展贡献一份力量。</div> </div> <div class="container clearfix layout_292464"> <div class="column"> <div class="col-md-3 layout_694949"> <div class="row column"> <div class="tag"> <dl class="foot-nav"> <dt><a href="/index.php?case=archive&act=list&catid=1" title="关于我们">关于我们</a><b></b></dt> <dd><a href="/index.php?case=archive&act=list&catid=4" title="平台介绍" target="_blank">平台介绍</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=11" title="团队成员" target="_blank">团队成员</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=12" title="发展历程" target="_blank">发展历程</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=7" title="职位招聘" target="_blank">职位招聘</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=19" title="送样须知" target="_blank">送样须知</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=20" title="常见问题" target="_blank">常见问题</a></dd> </dl> </div> </div> </div> <div class="col-md-3 layout_857626"> <div class="row column"> <div class="tag"> <dl class="foot-nav"> <dt><a href="/index.php?case=archive&act=list&catid=2" title="研究前沿">研究前沿</a><b></b></dt> <dd><a href="/index.php?case=archive&act=list&catid=13" title="行业资讯" target="_blank">行业资讯</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=10" title="技术方法" target="_blank">技术方法</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=6" title="文献资料" target="_blank">文献资料</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=8" title="数据共享" target="_blank">数据共享</a></dd> </dl> </div> </div> </div> <div class="col-md-3 layout_92919"> <div class="row column"> <div class="tag"> <dl class="foot-nav"> <dt><a href="/index.php?case=archive&act=list&catid=3" title="服务项目">服务项目</a><b></b></dt> <dd><a href="/index.php?case=archive&act=list&catid=15" title="超速离心" target="_blank">超速离心</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=16" title="电镜拍摄" target="_blank">电镜拍摄</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=17" title="粒径分析" target="_blank">粒径分析</a></dd> <dd><a href="/index.php?case=archive&act=list&catid=18" title="蛋白检测" target="_blank">蛋白检测</a></dd> </dl> </div> </div> </div> <div class="col-md-3 layout_87822"> <div class="row column"> <div class="tag"> <dl class="foot-nav"> <dt><a href="/index.php?case=archive&act=list&catid=5" title="联系我们">联系我们</a><b></b></dt> </dl> </div> </div> </div> <div class="clearfix layout_308983"> </div> </div> </div> <div class="container clearfix layout_760755"> <div class="column"> <div class="column layout_73459"> <div class="col-md-3"> <div class="row column"> <div class=" visual-contact visual-inline-block"> <p> 地 址：厦门市海沧区翁角西路生物医药产业园B2号楼1001</p> <p> 邮政编码：361000</p> <p> 电 话：0592-5792117</p> <p> 传 真：0592-5792117</p> <p> 手机：13599994885</p> <p> 邮 箱：info@ncell.com.cn</p> <p> 投诉邮 箱：info@ncell.com.cn</p> </div> </div> </div> <div class="col-md-6"> <div class="row column"> <div class=" visual-guestbook"> </div> </div> </div> <div class="col-md-3"> <div class="row column"> <div class="col-md-12 layout_199449 text-center"> <div class="row column"> <center> <img src="/html/upload/images/201904/15565910929476.png" class="img-responsive checkout" alt='' /> </center> </div> </div> <div class="clearfix layout_283216 text-center"> </div> </div> </div> </div> </div> </div> </div> </div> </div><div class="clearfix"></div> <!--foot --> <footer> <div class="foot"> <div class="container"> <div class="row"> <div class="copyright"> <p> Copyright ©<a href="http://www.ncell.com.cn" target="_blank">厦门恩赛尔生物科技有限公司（外泌体标准化服务平台）</a>,Inc.All rights reserved. <a href="/sitemap.html" target="_blank">网站地图</a> </p> <p> <a rel="nofollow" href="https://beian.miit.gov.cn" rel="nofollow" target="_blank">闽ICP备19009270号-1</a> Powered by <a href="https://www.cmseasy.cn" title="CmsEasy企业网站系统" target="_blank">CmsEasy</a> <a href="/index.php?case=archive&act=rss&catid=13">Rss</a></a> <script type="text/javascript"> <!-- document.writeln(" <a href='http://www.sgs.gov.cn/lz/licenselink.do>?nethod=licenceView&entyID=91350200M0000WK48R'><img src='/images/gongshang.png'></a> ") //--> </script> </p> </div> </div> </div> </footer> <!-- foot end --> <!-- search --> <div class="container-fluid"> <div class="modal fade bs-example-modal-lg-search" tabindex="-1" role="dialog" aria-labelledby="myLargeModalLabel"> <div class="modal-dialog modal-lg"> <div class="modal-content"> <div class="modal-header"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> <div class="blank5"></div> </div> <div class="row"> <form name='search' action="/index.php?case=archive&act=search" onsubmit="search_check();" method="post"> <div class="col-lg-1"></div> <div class="col-lg-10"> <div class="input-group"> <input type="text" name="keyword" class="form-control" placeholder="请输入查询信息！"> <span class="input-group-btn"> <button class="btn btn-default" name='submit' type="submit">搜索</button> </span> </div> </div> <div class="col-lg-1"></div> </form> </div> </div> </div> </div> <!-- search end --> <!-- shopping 购物车 --> <div class="modal fade bs-example-modal-lg-shopping" tabindex="-1" role="dialog" aria-labelledby="mySmallModalLabel"> <div class="modal-dialog modal-sm"> <div class="modal-content"> </div> </div> </div> <!-- s/shopping 购物车 --> <div class="servers"> <!--[if (gte IE 7)|!(IE)]><!--> <!-- 在线客服 --> <style type="text/css"> .izl-rmenu{position:fixed; left:0; margin-right:20px; bottom:0px; padding-bottom:0px; z-index:999; } .izl-rmenu .sbtn{width:72px; height:73px; margin-bottom:1px; cursor:pointer; position:relative;} .izl-rmenu .btn-qq{background:url(/template/default_visual/skin/images/servers/metro_color/r_qq.png) 0px 0px no-repeat; background-color:#999;color:#FFF;} .izl-rmenu .btn-qq:hover{background-color:#444;color:#FFF;} .izl-rmenu .btn-qq .qq{background-color:#444; position:absolute; width:160px; right:-160px; top:0px; line-height:73px; color:#FFF; font-size:18px; text-align:center; display:none;} .izl-rmenu .btn-qq a {color:#FFF;font-size:14px;} .izl-rmenu .btn-wx{background:url(/template/default_visual/skin/images/servers/metro_color/r_wx.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-wx:hover{background-color:#444;} .izl-rmenu .btn-wx .pic{position:absolute; right:-160px; top:0px; display:none;width:140px;height:140px;} .izl-rmenu .btn-phone{background:url(/template/default_visual/skin/images/servers/metro_color/r_phone.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-phone:hover{background-color:#444;} .izl-rmenu .btn-phone .phone{background-color:#ff811b; position:absolute; width:160px; right:-160px; top:0px; line-height:73px; color:#FFF; font-size:18px; text-align:center; display:none;} .izl-rmenu .btn-ali{background:url(/template/default_visual/skin/images/servers/metro_color/r_ali.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-ali:hover{background-color:#444;} .izl-rmenu a.btn-ali,.izl-rmenu a.btn-ali:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_ali.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-wangwang{background:url(/template/default_visual/skin/images/servers/metro_color/r_wangwang.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-wangwang:hover{background-color:#444;} .izl-rmenu a.btn-wangwang,.izl-rmenu a.btn-wangwang:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_wangwang.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-skype{background:url(/template/default_visual/skin/images/servers/metro_color/r_skype.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-skype:hover{background-color:#444;} .izl-rmenu a.btn-skype,.izl-rmenu a.btn-skype:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_skype.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-web{background:url(/template/default_visual/skin/images/servers/metro_color/r_web.png) 0px 0px no-repeat; background-color:#999;} .izl-rmenu .btn-web:hover{background-color:#444;} .izl-rmenu a.btn-web,.izl-rmenu a.btn-web:visited{background:url(/template/default_visual/skin/images/servers/metro_color/r_web.png) 0px 0px no-repeat; background-color:#999; text-decoration:none; display:block;} .izl-rmenu .btn-top{background:url(/template/default_visual/skin/images/servers/metro_color/r_top.png) 0px 0px no-repeat; background-color:#999; display:none;} .izl-rmenu .btn-top:hover{background-color:#444;} </style> <script language="javascript" type="text/javascript"> $(function(){ var tophtml="<div id=\"izl_rmenu\" class=\"izl-rmenu\"><div class=\"sbtn btn-qq\"><div class=\"qq\"><a rel=\"nofollow\" target=\"_blank\" href=\"tencent://Message/?Uin=226976731&websiteName=http://www.ncell.com.cn=&Menu=yes\">客服一</a><br /><a rel=\"nofollow\" target=\"_blank\" href=\"tencent://Message/?Uin=525274299&websiteName=http://www.ncell.com.cn=&Menu=yes\">客服二</a></div></div><div class=\"sbtn btn-wx\"><img class=\"pic\" src=\"/html/upload/images/201904/15565910929476.png\" onclick=\"window.location.href=\'http:\'\"/></div><div class=\"sbtn btn-phone\"><div class=\"phone\">0592-5792117</div></div><div class=\"sbtn btn-top\"></div></div>"; $("#top").html(tophtml); $("#izl_rmenu").each(function(){ $(this).find(".btn-qq").mouseenter(function(){ $(this).find(".qq").fadeIn("fast"); }); $(this).find(".btn-qq").mouseleave(function(){ $(this).find(".qq").fadeOut("fast"); }); $(this).find(".btn-wx").mouseenter(function(){ $(this).find(".pic").fadeIn("fast"); }); $(this).find(".btn-wx").mouseleave(function(){ $(this).find(".pic").fadeOut("fast"); }); $(this).find(".btn-phone").mouseenter(function(){ $(this).find(".phone").fadeIn("fast"); }); $(this).find(".btn-phone").mouseleave(function(){ $(this).find(".phone").fadeOut("fast"); }); $(this).find(".btn-top").click(function(){ $("html, body").animate({ "scroll-top":0 },"fast"); }); }); var lastRmenuStatus=false; $(window).scroll(function(){//bug var _top=$(window).scrollTop(); if(_top>200){ $("#izl_rmenu").data("expanded",true); }else{ $("#izl_rmenu").data("expanded",false); } if($("#izl_rmenu").data("expanded")!=lastRmenuStatus){ lastRmenuStatus=$("#izl_rmenu").data("expanded"); if(lastRmenuStatus){ $("#izl_rmenu .btn-top").slideDown(); }else{ $("#izl_rmenu .btn-top").slideUp(); } } }); }); </script> <div id="top"></div><![endif]--> <!-- 短信 --> </div> <div class="servers-wap"> <link href="/template/default_visual/skin/css/wap/wap6.css" rel="stylesheet" /> <style type="text/css"> #plug-wrap { position: fixed; top: 0; left: 0; width: 100%; height: 100%; background: rgba(0, 0, 0, 0); z-index:800; } .top_bar { position:fixed; bottom:0; right:0px; z-index:900; -webkit-tap-highlight-color: rgba(0, 0, 0, 0); font-family: Helvetica, Tahoma, Arial, Microsoft YaHei, sans-serif; } .plug-menu { -webkit-appearance:button; display:inline-block; width:36px; height:36px; border-radius:36px; position: absolute; bottom:17px; right: 17px; z-index:999; box-shadow: 0 0 0 4px #FFFFFF, 0 2px 5px 4px rgba(0, 0, 0, 0.25); -webkit-transition: -webkit-transform 200ms; -webkit-transform:rotate(1deg); color:#fff; background-image:url('/template/default_visual/skin/images/wao/plug.png'); background-repeat: no-repeat; -webkit-background-size: 80% auto; background-size: 80% auto; background-position: center center; } .plug-menu:before { font-size:20px; margin:9px 0 0 9px; } .plug-menu:checked { -webkit-transform:rotate(135deg); } .top_menu>li { width: 32px; height:32px; border-radius:32px; box-shadow: 0 0 0 3px #FFFFFF, 0 2px 5px 3px rgba(0, 0, 0, 0.25); position:absolute; bottom:0; right:0; margin-bottom: 20px; margin-right:20px; z-index:900; -webkit-transition: -webkit-transform 200ms; } .top_menu>li a { color:#fff; font-size:20px; display: block; height: 100%; line-height: 33px; text-align: center; } .top_menu>li>a label{ display:none; } .top_menu>li a img { display: block; width: 22px; height: 22px; text-indent: -999px; position: absolute; top: 50%; left: 50%; margin-top: -11px; margin-left: -11px; } .top_menu>li.on:nth-of-type(1) { -webkit-transform: translate(-0, -100px) rotate(720deg); } .top_menu>li.on:nth-of-type(2) { -webkit-transform: translate(-47px, -81px) rotate(720deg); } .top_menu>li.on:nth-of-type(3) { -webkit-transform: translate(-81px, -45px) rotate(720deg); } .top_menu>li.on:nth-of-type(4) { -webkit-transform: translate(-100px, 0) rotate(720deg); } #sharemcover { position: fixed; top: 0; left: 0; width: 100%; height: 100%; background: rgba(0, 0, 0, 0.7); display: none; z-index: 20000; } #sharemcover img { position: fixed; right: 18px; top: 5px; width: 260px; height: 180px; z-index: 20001; border:0; } </style> <div class="top_bar" style="-webkit-transform:translate3d(0,0,0)"> <nav> <ul id="top_menu" class="top_menu"> <input type="checkbox" id="plug-btn" class="plug-menu themeStyle" style="background-image:url('/template/default_visual/skin/images/wap/plug.png');border:0px;"> <li class="themeStyle out" style="background:"> <a href="tel:0592-5792117"><img src="/template/default_visual/skin/images/wap/plugmenu1.png"><label>电 话</label></a> </li> <li class="themeStyle out" style="background:"> <a href="sms:13599994885"><img src="/template/default_visual/skin/images/wap/plugmenu3.png"><label>短信</label></a> </li> <li class="themeStyle out" style="background:"> <a href="mqqwpa://im/chat?chat_type=wpa&uin=226976731&version=1&src_type=web&web_src=http://www.ncell.com.cn" id="btn_fenxiang"><img src="/template/default_visual/skin/images/wap/plugmenu5.png"><label>QQ号码</label></a> </li> <li class="themeStyle out" style="background:"> <a href="/index.php?case=guestbook&act=index"><img src="/template/default_visual/skin/images/wap/plugmenu6.png"><label>留言</label></a> </li> </ul> </nav> </div> <div id="plug-wrap" style="display: none;" ></div> <script> $(function(){ $(".plug-menu").click(function(){ var li = $(this).parents('ul').find('li'); if(li.attr("class") == "themeStyle on"){ li.removeClass("themeStyle on"); li.addClass("themeStyle out"); }else{ li.removeClass("themeStyle out"); li.addClass("themeStyle on"); } }); }); </script> </div> <!-- 导航下拉缩小高度 --> <script type="text/javascript"> <!-- $(document).ready(function(){ $(window).scroll(function() { var top = $(".carousel-indicators,.visual-category-img").offset().top; //获取指定位置 var scrollTop = $(window).scrollTop(); //获取当前滑动位置 if(scrollTop > top){ //滑动到该位置时执行代码 $(".navbar").addClass("active"); }else{ $(".navbar").removeClass("active"); } }); }); $(function(){ var cubuk_seviye = $(document).scrollTop(); var header_yuksekligi = $('.navbar').outerHeight(); $(window).scroll(function() { var kaydirma_cubugu = $(document).scrollTop(); if (kaydirma_cubugu > header_yuksekligi){$('.navbar').addClass('gizle');} else {$('.navbar').removeClass('gizle');} if (kaydirma_cubugu > cubuk_seviye){$('.navbar').removeClass('sabit');} else {$('.navbar').addClass('sabit');} cubuk_seviye = $(document).scrollTop(); }); }); //--> </script> <!-- 鼠标滑过展开一级菜单/一级菜单可点击 --> <script type="text/javascript"> $(function () { $(".dropdown,.dropdown-submenu").mouseover(function () { $(this).addClass("open"); }); $(".dropdown,.dropdown-submenu").mouseleave(function(){ $(this).removeClass("open"); }) }); $(document).ready(function(){ var _width = $(window).width(); if(_width < 768){ $("#navbar a.toogle").click(function(){ event.preventDefault(); }); } }); </script> <!-- wow动态效果 --> <link rel="stylesheet" href="/template/default_visual/skin/css/animate.min.css" /> <script src="/template/default_visual/skin/js/wow.min.js"></script> <script> if (!(/msie [6|7|8|9]/i.test(navigator.userAgent))){ new WOW().init(); }; </script> <!-- 导航置顶CSS --> <style type="text/css"> .navbar { padding-right:0; padding-left:0;position:fixed; right:0; left:0; z-index:1030; border-radius:0; } @media (max-width: 768px) { #bootstrap-touch-slider {margin-top:62px;} #navbar {margin-top:62px;} .navbar>.container .navbar-brand, .navbar>.container-fluid .navbar-brand {margin-left:0px;} } @media (max-width: 468px) { #bootstrap-touch-slider {margin-top:62px;} } </style> <script> $(document).ready(function() { $("#owl-demo").owlCarousel({ items : 3, lazyLoad : true, navigation : true }); }); </script> <!-- Bootstrap core Javascript ================================================== --> <!-- Placed at the end of the document so the pages load faster --> <script src="/template/default_visual/skin/js/bootstrap.min.js"></script> <!-- Just to make our placeholder images work. Don't actually copy the next line! --> <script src="/template/default_visual/skin/js/holder.min.js"></script> <!-- IE10 viewport hack for Surface/desktop Windows 8 bug --> <script src="/template/default_visual/skin/js/ie10-viewport-bug-workaround.js"></script> <script src="/template/default_visual/skin/js/bootstrap-submenu.js"></script> <!--[if lt IE 9]><!--> <script src="/template/default_visual/skin/js/ie/html5shiv.min.js"></script> <script src="/template/default_visual/skin/js/ie/respond.min.js"></script> <![endif]--> <!-- 图片滚动 --> <link href="/js/carousel/css/owl.carousel.css" rel="stylesheet"> <script src="/js/carousel/owl.carousel.min.js"></script> <script> $(document).ready(function() { $("#owl-demo1").owlCarousel({ items : 3, lazyLoad : true, navigation : true }); }); </script> <script> $(document).ready(function() { $("#owl-demo-friendlink-logo").owlCarousel({ items : 3, lazyLoad : true, navigation : true }); }); </script> <!-- 幻灯 --> <script src="/template/default_visual/skin/js/slide/jquery.touchSwipe.min.js"></script> <script src="/template/default_visual/skin/js/slide/bootstrap-touch-slider.js"></script> <!-- 繁简切换 --> <script type="text/javascript" src="/js/common.js"></script> <!-- 左侧树形菜单 --> <link rel="stylesheet" href="/js/left_menu_list/left_menu_list.css"> <script src="/js/left_menu_list/left_menu_list.js"></script> <!-- 内容切换图片 --> <link href="/template/default_visual/skin/js/lightgallery/css/lightgallery.css" rel="stylesheet"> <script src="/template/default_visual/skin/js/lightgallery/js/lightgallery.min.js"></script> <script src="/template/default_visual/skin/js/lightgallery/js/lg-pager.min.js"></script> <script src="/template/default_visual/skin/js/lightgallery/js/lg-fullscreen.min.js"></script> <script src="/template/default_visual/skin/js/lightgallery/js/lg-zoom.min.js"></script> <script src="/template/default_visual/skin/js/lightgallery/js/lg-hash.min.js"></script> <script> lightGallery(document.getElementById('lightgallery')); </script> <!-- 内容文字大小 --> <script src="/template/default_visual/skin/js/c_tool.js"></script> <!-- 幻灯支持手势滑动 --> <script type="text/javascript"> $('#bootstrap-touch-slider').bsTouchSlider(); </script> </body> </html>