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href="/index.php?case=archive&act=list&catid=14">案例展示</a></li> </ol> </nav> <div class="clearfix"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_338152"> <div class="row column"> <div class="clearfix"> </div> <div class="container clearfix layout_392307"> <div class="row column"> <div class="column"> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=42" class="img-auto"><img alt="通过表面增强拉曼光谱数据模式分析对外泌体进行分类用于肺癌诊断" src="/html/upload/images/201904/15563551903129.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563551903129.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-20</p> <h4> <a title="通过表面增强拉曼光谱数据模式分析对外泌体进行分类用于肺癌诊断" href="/index.php?case=archive&act=show&aid=42" target="_blank">通过表面增强拉曼光谱数据模式分析对外泌体进行分类用于肺癌诊断</a> </h4> <p> 不同于传统方法读取不同的峰位置和频谱幅度，本文通过主成分分析（PCA）对外泌体的整个SERS光谱进行分析。通过这种模式分析，将肺癌细胞衍生的外泌体明显区别于正常细胞衍生的外泌体，灵敏度为95.3％，特异性为97.3％。此外，通过分析PCA结果，研究人员认为这种差异是由来自肺癌细胞衍生的外泌体的SERS信号中的11个不同…<a href="/index.php?case=archive&act=show&aid=42" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=33" class="img-auto"><img alt="外泌体LncRNA促进肿瘤细胞耐药性" src="/html/upload/images/201904/15563525325623.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563525325623.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-20</p> <h4> <a title="外泌体LncRNA促进肿瘤细胞耐药性" href="/index.php?case=archive&act=show&aid=33" target="_blank">外泌体LncRNA促进肿瘤细胞耐药性</a> </h4> <p> 本文阐述了疾病相关LncRNA参与肾癌耐药性及通过外泌体传播的生理机制。…<a href="/index.php?case=archive&act=show&aid=33" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=41" class="img-auto"><img alt="树突状细胞衍生的外泌体在本体肝细胞癌小鼠模型中引发肿瘤消退" src="/html/upload/images/201904/15563550195572.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563550195572.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-20</p> <h4> <a title="树突状细胞衍生的外泌体在本体肝细胞癌小鼠模型中引发肿瘤消退" href="/index.php?case=archive&act=show&aid=41" target="_blank">树突状细胞衍生的外泌体在本体肝细胞癌小鼠模型中引发肿瘤消退</a> </h4> <p> 树突状细胞衍生的外泌体在本体肝细胞癌小鼠模型中引发肿瘤消退…<a href="/index.php?case=archive&act=show&aid=41" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=35" class="img-auto"><img alt="脂肪来源的干细胞分泌外泌体可减轻脂肪炎症和肥胖现象" src="/html/upload/images/201904/15563529559587.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563529559587.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-16</p> <h4> <a title="脂肪来源的干细胞分泌外泌体可减轻脂肪炎症和肥胖现象" href="/index.php?case=archive&act=show&aid=35" target="_blank">脂肪来源的干细胞分泌外泌体可减轻脂肪炎症和肥胖现象</a> </h4> <p> 在这项研究中，来自山东大学基础医学院的研究人员利用外泌体mRNA测序技术，研究来自WAT的ADSCs分泌外泌体使巨噬细胞向表达高水平的Arg-1和IL-10的M2极化。本文阐述了一种全新的外泌体介导的ADSCs巨噬细胞级联干扰机制，促进 WAT 通路免疫反应及代谢稳态，从而为肥胖和糖尿病患者提供潜在的治疗方案。…<a href="/index.php?case=archive&act=show&aid=35" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=39" class="img-auto"><img alt="多参数血浆EV分析有助于胰腺恶性肿瘤诊断" src="/html/upload/images/201904/15563542946629.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563542946629.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-15</p> <h4> <a title="多参数血浆EV分析有助于胰腺恶性肿瘤诊断" href="/index.php?case=archive&act=show&aid=39" target="_blank">多参数血浆EV分析有助于胰腺恶性肿瘤诊断</a> </h4> <p> 研究人员使用先进的多功能等离子体检测法来分析100多个临床患者中的循环肿瘤衍生的细胞外囊泡（tEV）。通过基于EV的蛋白标记物分析，确定了用于PDAC检测的五个标记物（PDAC EV标记物）。…<a href="/index.php?case=archive&act=show&aid=39" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=32" class="img-auto"><img alt="大脑创伤外泌体中环状RNA变化的研究" src="/html/upload/images/201904/15563522064902.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563522064902.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-15</p> <h4> <a title="大脑创伤外泌体中环状RNA变化的研究" href="/index.php?case=archive&act=show&aid=32" target="_blank">大脑创伤外泌体中环状RNA变化的研究</a> </h4> <p> 近期，天津医科大学总医院张建宁教授带领的神经创伤团队针对大脑创伤的研究，应用全转录组测序技术，仅通过大脑创伤外泌体中环状RNA表达谱研究发表了世界首个小鼠脑创伤模型外泌体环状RNA研究成果。…<a href="/index.php?case=archive&act=show&aid=32" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=31" class="img-auto"><img alt="脂肪组织巨噬细胞分泌外泌体 miRNA可大幅改善体内胰岛素敏感性" src="/html/upload/images/201904/15563516185774.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563516185774.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-15</p> <h4> <a title="脂肪组织巨噬细胞分泌外泌体 miRNA可大幅改善体内胰岛素敏感性" href="/index.php?case=archive&act=show&aid=31" target="_blank">脂肪组织巨噬细胞分泌外泌体 miRNA可大幅改善体内胰岛素敏感性</a> </h4> <p> 美国加州大学圣地亚哥分校Olefsky团队和中国医学科学院的研究者们，通过研究发现脂肪组织巨噬细胞（adipose tissue macrophages，ATMs）分泌的外泌体中含有miRNA并可以转移到胰岛素的靶细胞中，从而调节靶细胞对胰岛素的敏感性以及体内的总糖代谢稳态。…<a href="/index.php?case=archive&act=show&aid=31" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=40" class="img-auto"><img alt="血清细胞外囊泡含有原发性硬化性胆管炎和胆管癌的蛋白生物标志物" src="/html/upload/images/201904/15563546924613.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563546924613.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-15</p> <h4> <a title="血清细胞外囊泡含有原发性硬化性胆管炎和胆管癌的蛋白生物标志物" href="/index.php?case=archive&act=show&aid=40" target="_blank">血清细胞外囊泡含有原发性硬化性胆管炎和胆管癌的蛋白生物标志物</a> </h4> <p> 血清细胞外囊泡含有原发性硬化性胆管炎和胆管癌的蛋白生物标志物…<a href="/index.php?case=archive&act=show&aid=40" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=34" class="img-auto"><img alt="肿瘤缺氧环境促进外泌体癌症LncRNA高表达" src="/html/upload/images/201904/15563527223434.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563527223434.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-08</p> <h4> <a title="肿瘤缺氧环境促进外泌体癌症LncRNA高表达" href="/index.php?case=archive&act=show&aid=34" target="_blank">肿瘤缺氧环境促进外泌体癌症LncRNA高表达</a> </h4> <p> 本文证实缺氧膀胱癌细胞通过分泌富含致癌性LncRNA-UCA1的外泌体到肿瘤微环境中，促进肿瘤的生长和发育。并且，人血清外泌体LncRNA-UCA1具有作为膀胱癌诊断生物标志物的可能性。…<a href="/index.php?case=archive&act=show&aid=34" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=36" class="img-auto"><img alt="血液外泌体miRNA作为非小细胞癌分子标志物分析" src="/html/upload/images/201904/15563531721387.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563531721387.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-04-06</p> <h4> <a title="血液外泌体miRNA作为非小细胞癌分子标志物分析" href="/index.php?case=archive&act=show&aid=36" target="_blank">血液外泌体miRNA作为非小细胞癌分子标志物分析</a> </h4> <p> 本文发现腺癌（AC）和鳞癌（SCC）患者的血浆可分离出肿瘤来源外泌体，其中外泌体miRNA极有希望用于NSCLC早期预测和诊断。…<a href="/index.php?case=archive&act=show&aid=36" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=38" class="img-auto"><img alt="外泌体环状RNA表达具有癌症分子标志物特点" src="/html/upload/images/201904/15563538699410.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563538699410.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-03-15</p> <h4> <a title="外泌体环状RNA表达具有癌症分子标志物特点" href="/index.php?case=archive&act=show&aid=38" target="_blank">外泌体环状RNA表达具有癌症分子标志物特点</a> </h4> <p> 研究人员首先分离得到了来自于 MHCC-LM3 肝癌细胞的外泌体并对其进行了环状RNA测序。发现exosomes中的circRNA比exosomes来源细胞中的circRNA丰富得多。研究者把exosomes中的circRNA称为exo-circRNA。exo-circRNA代表外泌体中的一种新类型RNA，它最大的特性……<a href="/index.php?case=archive&act=show&aid=38" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="row news-list-text-pic"> <div class="col-md-2"> <a target="_blank" href="/index.php?case=archive&act=show&aid=37" class="img-auto"><img alt="尿液中的外泌体可作为往后液体活检的分子标志物" src="/html/upload/images/201904/15563533754361.jpg" onerror="this.src="{config::get(" class="img-responsive" data-src="/html/upload/images/201904/15563533754361.jpg" /></a> </div> <div class="col-md-10"> <p> 2019-02-15</p> <h4> <a title="尿液中的外泌体可作为往后液体活检的分子标志物" href="/index.php?case=archive&act=show&aid=37" target="_blank">尿液中的外泌体可作为往后液体活检的分子标志物</a> </h4> <p> 在这项研究中，来自美国国立卫生研究院的研究人员利用质谱等技术研究发现人类尿液外泌体中有295中蛋白，其中有许多蛋白与已报道的肾脏疾病密切相关。本文为往后的液体活检提供了新的诊断方案。…<a href="/index.php?case=archive&act=show&aid=37" target="_blank">[了解更多]</a> </p> </div> </div> <div class="blank10"> </div> <div class="clearfix"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_296434"> <div class="row column"> <div class="container clearfix layout_480985"> <div class="row column"> <div 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