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</div> <div class="container-fluid clearfix layout_564394 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0); margin-top: 30px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_439253"> <div class="column"> <div class="column visual-conent-title"> <p class="content-title"> 通过表面增强拉曼光谱数据模式分析对外泌体进行分类用于肺癌诊断</p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_610181" style="margin-top: 0px;"> <div class="column"> <div class="container clearfix layout_148235 text-center text-bold" style="font-size: 20px; color: rgb(0, 0, 0);"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_369638 text-center" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_13448"> <div class="column"> <div class="col-md-12 layout_455380"> <div class="col-md-2 column"> </div> <div class="col-md-8 column"> <div class="column visual-conent-author visual-inline-block"> <p class="content-author"> <span>作者：</span>admin</p> </div> <div class="column visual-conent-adddate visual-inline-block" style="padding-left: 15px; padding-right: 15px;"> <p class="content-adddate"> <span>添加时间：</span>2019-04-20 13:12:58</p> </div> <div class="column visual-conent-source visual-inline-block"> <p class="content-source"> <span>来源：</span>永诺生物</p> </div> <div class="column visual-category-statistics visual-inline-block" style="padding-left: 15px;"> 浏览：<script src="/index.php?case=archive&act=view_js&aid=42"></script></div> </div> <div class="col-md-2 column"> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_617573" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_903271"> <div class="column"> <div class="column visual-category-title"> <div class="content_tools_box"> <p class="content_tools"> <a href="javascript:CallPrint('print');">打印本文</a> <a href="javascript:doZoom(14)">小</a> <a href="javascript:doZoom(18)">中</a> <a href="javascript:doZoom(20)">大</a> </p> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_43304" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_784828"> <div class="column"> <div class="column visual-conent"> <p><strong>题目</strong>：Exosome Classification by Pattern Analysis of Surface-enhanced Raman Spectroscopy Data for Lung Cancer Diagnosis</p><p><strong>期刊</strong>：Analytical Chemistry</p><p><strong>影响因子</strong>：5.886</p><p><strong>简介</strong>：由于外泌体作为细胞间通讯的介质，特别是在癌症转移中，证据一直被积累，外泌体可以用作癌症的非侵入性指标。因此，已有几项应用外泌体的研究，用于开发癌症诊断方法，如ELISA测定。然而，由于需要标记过程和高浓度的外泌体，获得可靠的结果仍然具有挑战性。本研究中，通过组合表面增强拉曼散射（SERS）和统计模式分析来研究外泌体的无标签和高敏感的分类方法。</p><p>不同于传统方法读取不同的峰位置和频谱幅度，通过主成分分析（PCA）对外泌体的整个SERS光谱进行分析。通过这种模式分析，将肺癌细胞衍生的外泌体明显区别于正常细胞衍生的外泌体，灵敏度为95.3％，特异性为97.3％。此外，通过分析PCA结果，研究人员认为这种差异是由来自肺癌细胞衍生的外泌体的SERS信号中的11个不同点引起的。这一结果为外泌体作为癌症标志物对肺癌进行实时诊断和分类铺平了道路。</p><p style="text-align: center;"><img src="/html/upload/images/201904/15563551049844.png" width="695" height="412"/></p></div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_676599" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_158624"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_667472"> <div class="column"> <div class="container clearfix layout_381979"> <div class="column"> <div class=" 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</div> <div class="container-fluid clearfix layout_815628" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_771703"> <div class="column"> <div class="hr"> </div> </div> </div> </div> </div> <div class="container-fluid clearfix layout_275539" style="margin-top: 15px; margin-bottom: 15px;"> <div class="column"> <div class="container clearfix layout_875600"> <div class="column"> <div class="column visual-conent-relevant-list"> <h3> <a><a href='/index.php?case=tag&act=show&tag=%E5%A4%96%E6%B3%8C%E4%BD%93' target='_blank'>外泌体</a> <a href='/index.php?case=tag&act=show&tag=%E8%82%BA%E7%99%8C' target='_blank'>肺癌</a> <a href='/index.php?case=tag&act=show&tag=%E6%8B%89%E6%9B%BC%E5%85%89%E8%B0%B1' target='_blank'>拉曼光谱</a> <small>相关内容</small></a> </h3> <span>——</span> <hr class="featurette-divider" /> <div class="container list-container"> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>21</span> <p> 2019-03</p> </div> <h4> <a title=""新宠"外泌体正式进入临床检验，路还有多远？" href="/index.php?case=archive&act=show&aid=65" target="_blank">"新宠"外泌体正式进…</a> </h4> <p> 一管血检测癌症，是全球医学界共同的梦想。液体活检作为传统活检的替代技术，通过非侵入性的取样方式获得肿瘤信息，辅助癌症治疗，是精准医疗代表性的诊断技术。液体活检的主要检测物包括血液中的循环肿瘤细胞(circulating tumor cells，CTCs)、循环肿瘤DNA(circ… <a href="/index.php?case=archive&act=show&aid=65" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-01</p> </div> <h4> <a title="2018外泌体重量级研究一览，看这篇就够了" href="/index.php?case=archive&act=show&aid=64" target="_blank">2018外泌体重量级研究一览，看这篇就够</a> </h4> <p> 刚过去的2018年，也是外泌体研究热度持续升温的一年，在多个领域均涌现了重大的研究进展。本篇结合Nature、Cell、Cell Metab、Gastroenterology、Science、Nat Rev Mol Cell Biol、Chem Rev发表的重量级文章对2018外…… <a href="/index.php?case=archive&act=show&aid=64" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>20</span> <p> 2019-04</p> </div> <h4> <a title="2019年恩赛尔正式推出外泌体标准化服务" href="/index.php?case=archive&act=show&aid=50" target="_blank">2019年恩赛尔正式推出外泌体标准化服务</a> </h4> <p> 2019年4月厦门恩赛尔生物科技有限公司正式完成平台升级与系统完善，面向工业客户提供标准化的外泌体分离提纯及检测服务。… <a href="/index.php?case=archive&act=show&aid=50" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>01</span> <p> 2019-02</p> </div> <h4> <a title="2018年ncell参与外泌体行业共识制定" href="/index.php?case=archive&act=show&aid=49" target="_blank">2018年ncell参与外泌体行业共识制</a> </h4> <p> 2018年12月公司首席科学家叶国栋博士作为执笔人参与国内首个外泌体行业共识的制定与发布。… <a href="/index.php?case=archive&act=show&aid=49" target="_blank">[了解更多]</a> </p> </div> <div class="news-list list-border list-border-w"> <div class="list-date"> <span>11</span> <p> 2019-04</p> </div> <h4> <a title="Exosome：揭秘干细胞与免疫细胞如何“对话”" href="/index.php?case=archive&act=show&aid=48" target="_blank">Exosome：揭秘干细胞与免疫细胞如何</a> </h4> <p> 在此网络研讨会中，Pluchino博士讲解了外泌体与神经干细胞和神经元前体细胞发生信号传导的情况，以及它们在神经炎性疾病中的作用。此外，他还谈及外泌体靶向治疗的未来。… <a href="/index.php?case=archive&act=show&aid=48" target="_blank">[了解更多]</a> </p> </div> </div> <div class="clearfix"> </div> </div> </div> </div> </div> </div> </div> <div class="view-html"> <div class="container-fluid clearfix layout_971667" style="padding-top: 60px; padding-bottom: 60px; background-color: rgb(51, 51, 51); color: rgb(255, 255, 255);"> <div class="column"> <div class="container clearfix layout_976890 text-bold" style="font-size: 20px; padding-top: 20px; padding-bottom: 20px;"> <div class="column"> 厦门恩赛尔生物科技有限公司位于国家级企业孵化基地海沧生物医药产业园，参照GMP标准建设有完善的研发生产实验室并通过厦门市食品药品质量检查研究院依据国家标准GB50457-2008的洁净级别检测，团队汇聚大帮技术精湛的博士、硕士人员及外籍科学家，并由多名“千人计划”专家作为技术顾问，同时兼具遗传咨询师、系统架构师、注册审核员等各类人才，具备专业的科学研究和服务咨询能力。 企业定位为工业客户提供标准化的外泌体分离提纯及检测服务，并且在该项技术领域拥有创新突破和权威认可，作为首席科学家兼企业法人代表，叶国栋博士在肿瘤及血液检测技术领域有十数年的技术积累，参与并执笔国内首个《外泌体研究、转化和临床应用专家共识》，未来将继续促进该项标准化技术的落地，为外泌体行业的蓬勃发展贡献一份力量。</div> </div> <div class="container clearfix layout_292464"> <div class="column"> <div class="col-md-3 layout_694949"> <div class="row 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rel=\"nofollow\" target=\"_blank\" href=\"tencent://Message/?Uin=525274299&websiteName=http://www.ncell.com.cn=&Menu=yes\">客服二</a></div></div><div class=\"sbtn btn-wx\"><img class=\"pic\" src=\"/html/upload/images/201904/15565910929476.png\" onclick=\"window.location.href=\'http:\'\"/></div><div class=\"sbtn btn-phone\"><div class=\"phone\">0592-5792117</div></div><div class=\"sbtn btn-top\"></div></div>"; $("#top").html(tophtml); $("#izl_rmenu").each(function(){ $(this).find(".btn-qq").mouseenter(function(){ $(this).find(".qq").fadeIn("fast"); }); $(this).find(".btn-qq").mouseleave(function(){ $(this).find(".qq").fadeOut("fast"); }); $(this).find(".btn-wx").mouseenter(function(){ $(this).find(".pic").fadeIn("fast"); }); $(this).find(".btn-wx").mouseleave(function(){ $(this).find(".pic").fadeOut("fast"); }); $(this).find(".btn-phone").mouseenter(function(){ $(this).find(".phone").fadeIn("fast"); }); $(this).find(".btn-phone").mouseleave(function(){ 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<nav> <ul id="top_menu" class="top_menu"> <input type="checkbox" id="plug-btn" class="plug-menu themeStyle" style="background-image:url('/template/default_visual/skin/images/wap/plug.png');border:0px;"> <li class="themeStyle out" style="background:"> <a href="tel:0592-5792117"><img src="/template/default_visual/skin/images/wap/plugmenu1.png"><label>电 话</label></a> </li> <li class="themeStyle out" style="background:"> <a href="sms:13599994885"><img src="/template/default_visual/skin/images/wap/plugmenu3.png"><label>短信</label></a> </li> <li class="themeStyle out" style="background:"> <a href="mqqwpa://im/chat?chat_type=wpa&uin=226976731&version=1&src_type=web&web_src=http://www.ncell.com.cn" id="btn_fenxiang"><img src="/template/default_visual/skin/images/wap/plugmenu5.png"><label>QQ号码</label></a> </li> <li class="themeStyle out" style="background:"> <a href="/index.php?case=guestbook&act=index"><img src="/template/default_visual/skin/images/wap/plugmenu6.png"><label>留言</label></a> </li> </ul> </nav> </div> <div id="plug-wrap" style="display: none;" ></div> <script> $(function(){ $(".plug-menu").click(function(){ var li = $(this).parents('ul').find('li'); if(li.attr("class") == "themeStyle on"){ li.removeClass("themeStyle on"); li.addClass("themeStyle out"); }else{ li.removeClass("themeStyle out"); li.addClass("themeStyle on"); } }); }); </script> </div> <!-- 导航下拉缩小高度 --> <script type="text/javascript"> <!-- $(document).ready(function(){ $(window).scroll(function() { var top = $(".carousel-indicators,.visual-category-img").offset().top; //获取指定位置 var scrollTop = $(window).scrollTop(); //获取当前滑动位置 if(scrollTop > top){ //滑动到该位置时执行代码 $(".navbar").addClass("active"); }else{ $(".navbar").removeClass("active"); } }); }); $(function(){ var cubuk_seviye = $(document).scrollTop(); var header_yuksekligi = $('.navbar').outerHeight(); $(window).scroll(function() { var kaydirma_cubugu = $(document).scrollTop(); if (kaydirma_cubugu > header_yuksekligi){$('.navbar').addClass('gizle');} 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